Yoshiko Takahashi

This study identifies locus-specific DNA methylation defects at bivalent chromatin as a common feature in growth disorders caused by DNMT3A or NSD1 mutations.

This study shows that peristaltic movements drive gut elongation through collective cell rearrangements in chicken embryos.

The paper investigates how peristaltic wave origins in chicken embryos transition from random to organized positions through suppressive actions and lateral inhibition.

This study develops a contractile organoid model from chicken embryonic hindgut to study rhythm coordination between interstitial cells of Cajal and smooth muscle cells.

This study shows that the stiffness of primordial germ cells is required for their arrest and extravasation in avian embryos, with actin polymerization regulating this stiffness.

This paper develops a new anti-c-Kit antibody to identify interstitial cells of Cajal in chicken embryos and demonstrates its utility in visualizing ICCs in different gut layers.

The paper maps peristaltic wave origins along the chicken embryonic gut axis, revealing ENS regulation and inter-region cross-talk in gut development.

The paper identifies Sox2 gradient-regulated self-renewal and tubulogenesis in secondary neurulation-fated cells in the chicken tail bud.

This paper describes a method for spatio-temporally controlled gene manipulation in developing vasculature using lipid reagents and siRNA, showing successful knockdown of VE-cadherin without heart defects.

This study compares the 3-D patterns of parasympathetic nerves in mouse and chicken lungs during late development, revealing three key similarities in nerve distribution and function.