Author

Melanie Rodriguez

University of California, Santa BarbaraORCID 0000-0002-1599-2079Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Denise J. MontelliD· 2 shared Abhinava K. MishraiD· 1 shared Alison Marie TayloriD· 1 shared Alyse Ptacek· 1 shared Carlos Alfaro-Quinde· 1 shared Daniel GreineriD· 1 shared Elena KurudzaiD· 1 shared Emily KugelmanniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

Denise J. MontellORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rac2 Hyperactivity Drives Neutrophil Degranulation, Myeloperoxidase Deficiency, and Lymphopenia

H. Hanson, Melanie Rodriguez, Emily Kugelmann, Maria Malafei, Mitchell Boe, Denise J. Montell

This study identifies Rac2 hyperactivity as a cause of neutrophil dysfunction and T cell lymphopenia in patients with RAC2E62K mutations.

bioRxiv · May 15, 2026 · PreprintImmunology

NG2-targeting macrophages inhibit 3D invasion of patient-derived glioblastoma spheroids

Elena Kurudza, Sophia R.S. Varady, Daniel Greiner, James E. Marvin, Alyse Ptacek, Melanie Rodriguez, Abhinava K. Mishra, Gongping He, Gianpietro Dotti, Howard Colman, Melissa Quino Reeves, Denise J. Montell, Samuel Henry Cheshier, Minna Roh‐Johnson

This study shows NG2-targeting CAR-Ms engulf glioblastoma cells and block over 85% of their 3D invasion.

bioRxiv · Apr 7, 2026 · PreprintCancer Biology

Loss of Ing4 enhances hematopoietic regeneration in multipotent progenitor cells

Georgina A. Anderson, Marco Hernandex, Carlos Alfaro-Quinde, Zanshé Thompson, Melanie Rodriguez, Vera Binder, Alison Marie Taylor, Katie L. Kathrein

This study shows that loss of Ing4 promotes quiescence and transcriptional priming in multipotent progenitor cells, enhancing their regeneration capacity upon stress.

PLoS ONE · Feb 14, 2025Peer-reviewedMolecular Biology