NeuroscienceCell Death and DiseasePeer-reviewed
Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs
Carlo Brighi, Federico Salaris, Alessandro Soloperto…·Silvia Di Angelantonio
This study creates 2D and 3D human FXS models using FMRP-KO iPSCs, showing altered gene expression, impaired differentiation, and increased glial proliferation.
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