Author

Carlo Brighi

Italian Institute of TechnologyORCID 0000-0002-5729-2302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alessandro RosaiD· 1 shared Alessandro SolopertoiD· 1 shared Angelo M. ReggianiiD· 1 shared Chiara D’AntoniiD· 1 shared Federica CordellaiD· 1 shared Federico SalarisiD· 1 shared Maria RositoiD· 1 shared Pier Francesca PorcedduiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alessandro RosaORCID

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1 paper

Recent·Most cited

Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs

Carlo Brighi, Federico Salaris, Alessandro Soloperto, Federica Cordella, Silvia Ghirga, Valeria de Turris, Maria Rosito, Pier Francesca Porceddu, Chiara D’Antoni, Angelo M. Reggiani, Alessandro Rosa, Silvia Di Angelantonio

This study creates 2D and 3D human FXS models using FMRP-KO iPSCs, showing altered gene expression, impaired differentiation, and increased glial proliferation.

Cell Death and Disease · May 15, 2021Peer-reviewedNeuroscience