Maria Rosito

Vitamin D differentially modulates effector and regulatory T-cell migration across the blood-brain barrier

This study shows that vitamin D reduces effector T-cell migration across the blood-brain barrier while preserving regulatory T-cell entry, potentially benefiting multiple sclerosis patients.

Microglia control glutamatergic synapses in the adult mouse hippocampus

This study shows that microglia regulate glutamatergic synapses in adult mouse hippocampus, with their removal causing reversible synaptic and behavioral changes.

Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs

This study creates 2D and 3D human FXS models using FMRP-KO iPSCs, showing altered gene expression, impaired differentiation, and increased glial proliferation.

ALS-FUS mutation affects the activities of HuD/ELAVL4 and FMRP leading to axon phenotypes in motoneurons

This study shows that ALS-FUS mutations disrupt HuD/ELAVL4 and FMRP activities, leading to axon phenotypes in motoneurons through altered transcript stability.