Author

Louise J Newnham

University of SussexORCID 0000-0002-1627-5530Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alan H. HandysideiD· 2 shared Christian Simon OttoliniiD· 1 shared D HenningiD· 1 shared Dmitri A. PetroviD· 1 shared Eva R. HoffmanniD· 1 shared Jakub Horak· 1 shared Jan Pozdena· 1 shared Jan Velebny· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Alan H. HandysideORCID

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2 papers

Recent·Most cited

GeneticsScientific ReportsPeer-reviewedOct 22, 2025

Combined SNP parental haplotyping and intensity analysis identifies meiotic and mitotic aneuploidies and frequent segmental aneuploidies in preimplantation human embryos

Alan H. Handyside, Louise J Newnham, Matthew Newnham…·Jakub Horak

The paper combines SNP haplotyping and intensity analysis to identify meiotic and mitotic aneuploidies in preimplantation embryos, finding 37% aneuploidy rate with equal meiotic and mitotic cases.

8 citationstop 1%

humanwhole-genome sequencing

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GeneticsHuman Molecular GeneticsPeer-reviewedApr 20, 2018

Tripolar mitosis drives the association between maternal genotypes of PLK4 and aneuploidy in human preimplantation embryos

Rajiv C. McCoy, Louise J Newnham, Christian Simon Ottolini…·Alan H. Handyside

The paper identifies tripolar mitosis as a mechanism causing aneuploidy in human embryos and links it to maternal PLK4 genetic variants.

75 citationstop 4%

humanbulk RNA-seq

𝕏 PostBluesky