Author

Maria Sindeeva

AIRI - Artificial Intelligence Research InstituteORCID 0000-0002-1629-7756Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:variant effect prediction· 2 Assay:ChIP-seq· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:protein sequence· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Olga L. KardymoniD· 2 shared Tatiana ShashkovaiD· 2 shared Alexander LapiniD· 1 shared Dmitriy UmerenkoviD· 1 shared Elian Malkin· 1 shared Fedor NikolaeviD· 1 shared Manvel AvetisianiD· 1 shared Nikita BaranoviD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenetics

Olga L. KardymonORCID

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2 papers

Recent·Most cited

GeneticsGigaSciencePeer-reviewedJan 1, 2023

Cell type-specific interpretation of noncoding variants using deep learning-based methods

Maria Sindeeva, Nikolay Chekanov, Manvel Avetisian…·Veniamin Fishman

The paper introduces DeepCT, a deep learning model that predicts cell type-specific effects of noncoding variants by learning from sparse epigenetic data.

4 citations

humanDNA methylation

𝕏 PostBluesky

BioinformaticsbioRxivPreprintDec 25, 2022

PROSTATA: Protein Stability Assessment using Transformers

Dmitriy Umerenkov, Tatiana Shashkova, П. В. Страшнов…·Olga L. Kardymon

PROSTATA predicts protein stability changes from point mutations using a transformer-based model, outperforming existing neural network approaches.

7 citations

protein sequencetransformer / foundation model

𝕏 PostBluesky