Adeno-associated viruses escort nanomaterials to specific cells and tissues
Keisuke Nagao, Emmanuel Vargas Paniagua, Katherine Lei, Jacob L. Beckham, Peyton Worthington, Marie Manthey, Matthew Ye, Florian Koehler, Ye Ji Kim, Elian Malkin, Michika Onoda, Noah Kent, Shota Michida, Emily Crespin Guerra, Robert J. Macfarlane, Polina Anikeeva
This paper demonstrates that adeno-associated viruses can be coupled to nanoparticles to deliver them specifically to target tissues, with an example of brain-targeting using AAV serotype CAP-B10.
bioRxiv · Apr 4, 2025 · PreprintBioengineering