Diane Bissen

A hyperactivating mutation in formin-like 2 causes brain and vertebrae defects

This study identifies a hyperactivating mutation in Fmnl2 causing brain and vertebrae defects in mice through a forward genetics screen.

Prey capture learning drives critical period-specific plasticity in mouse binocular visual cortex

This study shows that prey capture learning during the critical period in mice enhances visual function through structural plasticity, including increased excitatory connectivity and spine turnover, which is absent in adults.

Rapid prey capture learning drives a slow resetting of network activity in rodent binocular visual cortex

This study shows that learning in juvenile rats leads to a slow increase in firing rates in V1b neurons, driven by homeostatic plasticity mechanisms.

Fully automated detection of dendritic spines in 3D live cell imaging data using deep convolutional neural networks

This paper develops a deep learning pipeline for automated dendritic spine detection in 3D live cell imaging data, achieving near-human performance without retraining.