Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs
David M. Kern, SeCheol Oh, Richard K. Hite, Stephen Graf Brohawn
The paper presents cryo-EM structures of LRRC8A in lipid nanodiscs with DCPIB inhibitor, revealing gating mechanisms and lipid-dependent structural changes.
eLife · Feb 18, 2019Peer-reviewedNeuroscience