Plasma Membrane Damage by Environmental Materials Enhances Cell-Cell Fusion and Impairs Immune Functions of Macrophages
Dandan Wu, Xing Zhang, Ruoning Wang, Amanda Livingston, Eliane El Hayek, Xiang Xue, Aaron K. Neumann, Matthew J. Campen, Meilian Liu, Xuexian O. Yang
This study shows that environmental materials damage macrophage plasma membranes, reducing ROS and phagocytosis while increasing cell fusion and impairing immune responses.
bioRxiv · Jun 17, 2025 · PreprintImmunology