Author

Takayoshi Masuoka

Kanazawa Medical UniversityORCID 0000-0002-1689-8762Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Hitomi NakazawaiD· 1 shared Ikunobu MuramatsuiD· 1 shared Junsuke UwadaiD· 1 shared Takashi YazawaiD· 1 shared Takeshi KiyoiiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Hitomi NakazawaORCID

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1 paper

Recent·Most cited

PIKFYVE inhibition induces endosome- and lysosome-derived vacuole enlargement via ammonium accumulation

Junsuke Uwada, Hitomi Nakazawa, Takeshi Kiyoi, Takashi Yazawa, Ikunobu Muramatsu, Takayoshi Masuoka

This study shows that PIKFYVE inhibition causes endosome and lysosome enlargement through ammonium accumulation from glutamine metabolism, impairing lysosomal function and autophagic flux.

Journal of Cell Science · Nov 26, 2024Peer-reviewedCell Biology