Author

Takeshi Kiyoi

Kanazawa Medical UniversityORCID 0000-0002-0842-1614Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Hitomi NakazawaiD· 1 shared Ikunobu MuramatsuiD· 1 shared Junsuke UwadaiD· 1 shared Takashi YazawaiD· 1 shared Takayoshi MasuokaiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Hitomi NakazawaORCID

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1 paper

Recent·Most cited

Cell BiologyJournal of Cell SciencePeer-reviewedNov 26, 2024

PIKFYVE inhibition induces endosome- and lysosome-derived vacuole enlargement via ammonium accumulation

Junsuke Uwada, Hitomi Nakazawa, Takeshi Kiyoi…·Takayoshi Masuoka

This study shows that PIKFYVE inhibition causes endosome and lysosome enlargement through ammonium accumulation from glutamine metabolism, impairing lysosomal function and autophagic flux.

22 citations

humanproteomics

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