Author

Mahraz Parvand

University of British ColumbiaORCID 0000-0002-1704-5331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

Alvaro Luna Cortes· 1 shared Catharine H. RankiniD· 1 shared Dawson Born· 1 shared Joseph LiangiD· 1 shared Tahereh BozorgmehriD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperNeuroscience

Alvaro Luna Cortes

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1 paper

Recent·Most cited

A Familial Alzheimers Disease Associated Mutation in Presenilin-1 Mediates Amyloid-Beta Independent Cell Specific Neurodegeneration

Mahraz Parvand, Joseph Liang, Tahereh Bozorgmehr, Dawson Born, Alvaro Luna Cortes, Catharine H. Rankin

This study shows that a familial Alzheimer's disease mutation in presenilin-1 causes cell-specific neurodegeneration in C. elegans independent of amyloid-beta, which is rescued by over-expression of wild-type human presenilin.

PLoS ONE · Sep 6, 2024Peer-reviewedNeuroscience