BiochemistrybioRxivPreprint
Crystallographic Fragment Screen of Coxsackievirus A16 2A Protease identifies new opportunities for the development of broad-spectrum anti-enterovirals
Ryan M. Lithgo, Charles W.E. Tomlinson, M. Fairhead…·F. von Delft
The paper identifies 75 fragments that bind to Coxsackievirus A16 2A protease, including 38 unique compounds in the active site, offering a path for broad-spectrum anti-enteroviral inhibitors.