Dennis D. Spencer

This study identifies somatic Ras-MAPK pathway variants in hippocampal tissue from patients with drug-resistant epilepsy, showing their association with clonal competition and worse surgical outcomes.

The paper introduces the connectivity index (CI) to grade epileptogenicity by analyzing evoked responses to electrical stimulation and finds higher CI in seizure onset zones compared to controls.

This study surveys current practices in presurgical language fMRI for epilepsy, finding significant variability in protocols, tasks, analysis methods, and expertise involvement.

This study surveys global epilepsy surgical programs on their use of presurgical language fMRI and reports mixed outcomes in localizing language cortex and predicting post-surgical function.