Qi Yan

The paper investigates how a Vibrio cholerae peptide binds lipids through a β-hairpin conformation, contributing to biofilm adhesion and host colonization.

The paper develops a DNA nanodevice to apply controlled forces to proteins, demonstrating its use in studying mechanosensitive protein interactions and identifying novel tension-dependent binders.

The paper shows that spatial clustering of piRNA genes in nematodes enhances transcription through phase separation involving UAD-2 and the SUMO regulatory factors GEI-17 and TOFU-3.

The paper introduces the connectivity index (CI) to grade epileptogenicity by analyzing evoked responses to electrical stimulation and finds higher CI in seizure onset zones compared to controls.

The paper identifies WAGO-4, a cytoplasmic Argonaute protein, as essential for the inheritance of RNAi in C. elegans, showing its role in translocating to the germline and binding 22G-RNAs.