Author

Martin Dufresne

Vanderbilt UniversityORCID 0000-0002-1731-3666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 4 Organism:human· 3 Assay:spatial transcriptomics· 3 Research Focus:cell type annotation· 2 Research Focus:spatial domain detection· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jeffrey M. SpragginsiD· 4 shared Raf Van de PlasiD· 4 shared Lukasz G. MigasiD· 3 shared Angela R.S. KruseiD· 2 shared Felipe A. MoseriD· 2 shared Jamie L. AlleniD· 2 shared Madeline E. ColleyiD· 2 shared Mark P. deCaesteckeriD· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersBioinformatics

Jeffrey M. SpragginsORCID

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Author profile →

4 papers

Recent·Most cited

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedJul 18, 2026

Multimodal Molecular Mapping of the Vasculature in Human Cortex Reveals Lipid Markers of Cerebral Amyloid Angiopathy

Cody R. Marshall, Felipe A. Moser, Claire F. Scott…·Jeffrey M. Spraggins

The paper maps lipid microenvironments in human brain vasculature using multimodal imaging and identifies lipid markers associated with cerebral amyloid angiopathy.

DOI 10.1186/s40478-026-02361-4

humanspatial transcriptomics

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BioinformaticsbioRxivPreprintDec 2, 2025

IsoSpace: Chemistry-Informed Dimensionality Reduction and Automated Isotope Candidate Detection in Imaging Mass Spectrometry

Meenakshi Meenakshi, Lukasz G. Migas, Katerina V. Djambazova…·Raf Van de Plas

IsoSpace provides a chemistry-informed dimensionality reduction method for imaging mass spectrometry that identifies isotopic patterns without prior assumptions.

DOI 10.64898/2025.11.30.691393

mouseimaging

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Molecular BiologybioRxivPreprintApr 7, 2025

A Multimodal Imaging Pipeline for the Discovery of Molecular Markers of Cellular Neighborhoods

Thai H. Pham, Melissa A. Farrow, Lukasz G. Migas…·Jeffrey M. Spraggins

The paper develops a multimodal imaging pipeline to identify molecular markers of cellular neighborhoods in human kidney tissue by integrating imaging mass spectrometry and immunofluorescence data.

4 citations

humanspatial transcriptomics

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJul 16, 2021

Automated Segmentation of Kidney Nephron Structures by Deep Learning Models on Label-free Autofluorescence Microscopy for Spatial Multi-omics Data Acquisition and Mining

Nathan Heath Patterson, Ellie L. Pingry, Felipe A. Moser…·Jeffrey M. Spraggins

14 citations

humanspatial transcriptomics

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