Author

Silvia Stacchiotti

Fondazione IRCCS Istituto Nazionale dei TumoriORCID 0000-0002-1742-8666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Nadia ZaffaroniiD· 2 shared Sandro PasqualiiD· 2 shared Valentina ZucoiD· 2 shared Albiruni R. Abdul Razak· 1 shared Alessandro GronchiiD· 1 shared Alex KentsisiD· 1 shared Anna Maria FrezzaiD· 1 shared Cesare SoffientiniiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Nadia ZaffaroniORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 4, 2026

Optimization of a Subcutaneous Epithelioid Hemangioendothelioma Xenograft Model for Evaluation of Preclinical Therapeutics

Zilu Chen, Lucy Wang, Valentina Zuco…·Christine Allen

This study optimizes a subcutaneous xenograft model for EHE using patient-derived cells, showing that low cell densities produce reproducible tumors sensitive to mTOR inhibition.

DOI 10.64898/2026.11.03.764004

mouseexperimental assay

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Cancer BiologybioRxivPreprintAug 4, 2026

Histone deacetylase activity limits the response to EZH2 inhibition-based therapy in epithelioid sarcoma and is targetable by epigenetic combination

Noemi Arrighetti, Cesare Soffientini, Valentina Zuco…·Sandro Pasquali

This paper identifies HDAC inhibition as a strategy to overcome resistance to EZH2 inhibitors in INI1-deficient epithelioid sarcoma by restoring H3K27 acetylation and enhancing therapeutic response.

1 citation

humanChIP-seq

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