Author

Cesare Soffientini

Fondazione IRCCS Istituto Nazionale dei TumoriORCID 0009-0007-0614-5402Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Sandro PasqualiiD· 2 shared Stefano PercioiD· 2 shared Alessandro GronchiiD· 1 shared Alex KentsisiD· 1 shared Anna Maria FrezzaiD· 1 shared Antonio Fernández-Aramburo· 1 shared Atanasio PandiellaiD· 1 shared Azucena Esparı́s-OgandoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Sandro PasqualiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 4, 2026

Histone deacetylase activity limits the response to EZH2 inhibition-based therapy in epithelioid sarcoma and is targetable by epigenetic combination

Noemi Arrighetti, Cesare Soffientini, Valentina Zuco…·Sandro Pasquali

This paper identifies HDAC inhibition as a strategy to overcome resistance to EZH2 inhibitors in INI1-deficient epithelioid sarcoma by restoring H3K27 acetylation and enhancing therapeutic response.

1 citation

humanChIP-seq

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Cancer BiologyInternational Journal of Biological SciencesPeer-reviewedFeb 4, 2026

VCAN is essential for ERK5-driven tumorigenesis in soft tissue sarcoma

Jaime Jiménez‐Suárez, Francisco J. Cimas, José Joaquín Paricio…·Ricardo Sánchez‐Prieto

This study identifies VCAN as a novel transcriptional target of ERK5 and shows its essential role in ERK5-driven tumorigenesis in soft tissue sarcoma.

1 citation

mousebulk RNA-seq

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