Developmental BiologyNature CommunicationsPeer-reviewed
CBP/EP300 acetylates and stabilizes the stress-responsive Heat Shock Factor 2, a process compromised in Rubinstein-Taybi syndrome
Aurélie de Thonel, Johanna K. Ahlskog, Kévin Daupin…·Valérie Mezger
The paper shows that CBP/EP300 acetylates and stabilizes HSF2, which is disrupted in Rubinstein-Taybi syndrome, leading to impaired heat shock response.
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