Author

Annie W. Shieh

Brown Foundation Institute of Molecular Medicine for the Prevention of Human DiseasesORCID 0000-0002-1770-5846Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:Ribo-seq· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Bingshan LiiD· 2 shared Chao CheniD· 2 shared Chunyu LiuiD· 2 shared Gina M. GiaseiD· 2 shared Kay S. Grennan· 2 shared Kevin P. WhiteiD· 2 shared Rui CheniD· 2 shared Sidney H. WangiD· 2 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Bingshan LiORCID

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3 papers

Recent·Most cited

GeneticsNature CommunicationsPeer-reviewedNov 28, 2025

The impact of common variants on gene expression in the human brain: from RNA to protein to schizophrenia risk

Qiuman Liang, Yi Jiang, Annie W. Shieh…·Sidney H. Wang

The paper identifies eQTLs, rQTLs, and pQTLs in the human brain and shows that many eQTL effects are attenuated post-transcriptionally, yet still correlate with schizophrenia GWAS signals.

8 citations

humanbulk RNA-seq

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GenomicsPLoS ONEPeer-reviewedNov 21, 2023

Transcriptome-wide profiling of acute stress induced changes in ribosome occupancy level using external standards

Annie W. Shieh, Sandeep Kumar Bansal, Zhen C. Zuo, Sidney H. Wang

This paper introduces spike-in oligomers for accurate ribosome profiling under acute stress and evaluates normalization methods for stress-induced translation changes.

2 citations

humanRibo-seq

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BioinformaticsPLoS Computational BiologyPeer-reviewedApr 13, 2020

DRAMS: A Tool to Detect and Re-Align Mixed-up Samples for Integrative Studies of Multi-omics Data

Yi Wei Jiang, Gina M. Giase, Kay S. Grennan…·Chunyu Liu

DRAMS detects and corrects sample mix-ups in multi-omics data by aligning genetic and omics data, improving statistical power and result quality.

11 citations

humanmultiome

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