The impact of common variants on gene expression in the human brain: from RNA to protein to schizophrenia risk
Qiuman Liang, Yi Jiang, Annie W. Shieh, Dan Zhou, Rui Chen, Feiran Wang, Meng Michelle Xu, Mingming Niu, Xusheng Wang, Dalila Pinto, Yue Wang, Lijun Cheng, Ramu Vadukapuram, Chunling Zhang, Kay S. Grennan, , Sidney H. Wang
The paper identifies eQTLs, rQTLs, and pQTLs in the human brain and shows that many eQTL effects are attenuated post-transcriptionally, yet still correlate with schizophrenia GWAS signals.
Nature Communications · Nov 28, 2025Peer-reviewedGenetics