Eric L. Weiss

Facile detection of peptide-protein interactions using an electrophoretic crosslinking shift assay

The paper introduces ECSA, an electrophoretic crosslinking shift assay, to detect low-affinity peptide-protein interactions, demonstrating its effectiveness with MAP kinase and D-motif peptides.

LiF-MS+, a revised technique for mapping peptide-protein interactions

LiF-MS+ improves peptide-protein interaction mapping by replacing the mass tag with a positively charged compound, enhancing detection of binding sites.