Author

Laura Marie Lombardi

ORCID 0000-0002-1793-7524Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Amara Greer-ShortiD· 2 shared Emilee Easter· 2 shared Kathryn N. IveyiD· 2 shared Timothy C. HoeyiD· 2 shared Ze ChengiD· 2 shared Ana BudaniD· 1 shared Anna Greenwood· 1 shared Charles Feathers· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Amara Greer-ShortORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintApr 20, 2026

In Vivo Rescue of Cardiomyopathy Through Cardiac Prime Editing

Wenjing Liang, Lindsey M. Rollosson, Emilee Easter…·Ze Cheng

This study demonstrates the use of in vivo prime editing to correct a cardiomyopathy-causing mutation in a humanized mouse model, rescuing disease phenotypes.

DOI 10.64898/2026.02.10.705148

mousehuman

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GeneticsNature CommunicationsPeer-reviewedMar 4, 2025

Gene Therapy Mediates Therapeutic Improvement in Cardiac Hypertrophy and Survival in a Murine Model of MYBPC3-Associated Cardiomyopathy

Amara Greer-Short, Anna Greenwood, Elena C. Leon…·Laura Marie Lombardi

This study demonstrates that AAV gene therapy with TN-201 restores MYBPC3 protein levels, reverses cardiac hypertrophy, and improves survival in a murine model of MYBPC3-associated HCM.

47 citationstop 1%

mouseexperimental assay

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