Ruiqing Fu

The paper investigates cfDNA fragmentation patterns in tumor models to distinguish between non-tumor cfDNA and ctDNA, finding differences in fragment length and site-specific variation.

This study uses single-cell RNA sequencing to analyze pediatric ependymoma subclonal heterogeneity and identifies gene expression patterns linked to patient survival.

The paper constructs a single-cell atlas of hematopoiesis and leukemogenesis, identifies leukemia subpopulations, and develops a composite index to predict clinical outcomes.