Author

Wenhong Hou

Southern University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Research Focus:gene regulatory network inference· 4 Organism:human· 4 Assay:scRNA-seq· 4 Research Focus:cell type annotation· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Ni HongiD· 3 shared Wenfei JiniD· 3 shared Pengfei QiniD· 2 shared Biao ZhangiD· 1 shared Bin SuiD· 1 shared Bin ZouiD· 1 shared Bing SuiD· 1 shared Changyuan Huang· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBioinformatics

Ni HongORCID

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4 papers

Recent·Most cited

Comprehensive mapping of the alternative polyadenylation site usage and its dynamics at single cell resolution

Junliang Wang, Wei Chen, Wenjun Yue, Wenhong Hou, Feng Rao, Hanbing Zhong, Yuanming Qi, Ni Hong, Ting Ni, Wenfei Jin

This study develops scPolyA-seq to analyze alternative polyadenylation at single cell resolution, finding that many genes use only one polyA site per cell and identifying cell cycle-related polyA site usage switches.

Proceedings of the National Academy of Sciences · Dec 1, 2022Peer-reviewedBioinformatics

Mesenchymal stem cell subpopulations and their heterogeneity of response to inductions revealed by single-cell RNA-seq

Wenhong Hou, Li Duan, Changyuan Huang, Xingfu Li, Xiao Gang Xu, Pengfei Qin, Ni Hong, Daping Wang, Wenfei Jin

The paper identifies MSC subpopulations and their differential responses to inductions using single-cell RNA-seq, revealing subtype-specific gene expression and differentiation potential.

Frontiers in Cell and Developmental Biology · Dec 17, 2021Peer-reviewedGenetics

Integrated decoding hematopoiesis and leukemogenesis at single-cell resolution and its clinical implication

Pengfei Qin, Yakun Pang, Wenhong Hou, Ruiqing Fu, Yingchi Zhang, Xuefei Julie Wang, Guofeng Meng, Qifa Liu, Xiaofan Zhu, Ni Hong, Tao Cheng, Wenfei Jin

The paper constructs a single-cell atlas of hematopoiesis and leukemogenesis, identifies leukemia subpopulations, and develops a composite index to predict clinical outcomes.

Cell Discovery · Jan 5, 2021Peer-reviewedGenomics

Large-scale single-cell analysis reveals critical immune characteristics of COVID-19 patients

Xianwen Ren, Wen Wen, Xiaoying Fan, Wenhong Hou, Bin Su, Pengfei Cai, Jiesheng Li, Yang Liu, Fei Tang, Fan Zhang, Yu Yang, Jiangping He, Wenji Ma, Jingjing He, Pingping Wang, , Zemin Zhang

This study uses single-cell RNA sequencing to analyze immune responses in COVID-19 patients, identifying key immune cell changes and molecular pathways linked to disease severity.

bioRxiv · Oct 29, 2020 · PreprintGenomics