The Hippo/YAP Pathway Mediates the De-differentiation of Corneal Epithelial Cells into Functional Limbal Epithelial Stem Cells In Vivo
Yijian Li, Lingling Ge, Bangqi Ren, Xue Zhang, Zhiyuan Yin, Hongling Liu, Yuli Yang, Yong Liu, Haiwei Xu
This study shows corneal epithelial cells can de-differentiate into functional limbal epithelial stem cells in vivo, mediated by the Hippo/YAP pathway, offering a new approach for treating limbal stem cell deficiency.
Investigative Ophthalmology & Visual Science · Nov 15, 2024Peer-reviewedCell Biology