Author

Yijian Li

Army Medical UniversityORCID 0000-0002-7619-8207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Baichen Ze· 1 shared Bangqi ReniD· 1 shared Bin KangiD· 1 shared Binyan YuiD· 1 shared Cheng‐Chi Chao· 1 shared Dan WangiD· 1 shared Fei WangiD· 1 shared Haiwei XuiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperGenetics

Baichen Ze

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Transcriptomic study of testicular hypoxia adaptation in Tibetan sheep

Binyan Yu, Yanan Yang, Yijian Li, Rong Gao, Min Ma, Xinrong Wang

This study identifies differentially expressed genes and pathways in Tibetan sheep testicular tissue under hypoxia, suggesting their role in reproductive adaptation to high altitude.

Reproduction in Domestic Animals · Mar 1, 2025Peer-reviewedGenomics

The Hippo/YAP Pathway Mediates the De-differentiation of Corneal Epithelial Cells into Functional Limbal Epithelial Stem Cells In Vivo

Yijian Li, Lingling Ge, Bangqi Ren, Xue Zhang, Zhiyuan Yin, Hongling Liu, Yuli Yang, Yong Liu, Haiwei Xu

This study shows corneal epithelial cells can de-differentiate into functional limbal epithelial stem cells in vivo, mediated by the Hippo/YAP pathway, offering a new approach for treating limbal stem cell deficiency.

Investigative Ophthalmology & Visual Science · Nov 15, 2024Peer-reviewedCell Biology

Selective targeting of an oncogenic KRAS mutant allele by CRISPR/Cas9 induces efficient tumor regression

Qianqian Gao, Wenjie Ouyang, Bin Kang, Xu Han, Ying Xiong, Renpeng Ding, Yijian Li, Fei Wang, Lei Huang, Lei Chen, Dan Wang, Xuan Dong, Zhao Zhang, Yanshan Li, Baichen Ze, , Cheng‐Chi Chao

This paper develops CRISPR systems to target and deplete an oncogenic KRAS mutant allele, leading to tumor regression in vitro and in vivo.

Theranostics · Jan 1, 2020Peer-reviewedGenetics