Author

Likun Hou

Tongji UniversityORCID 0000-0002-1797-8342Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:contrastive learning· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Chunyan WuiD· 1 shared Di WangiD· 1 shared Dongbo JiangiD· 1 shared Dongqing SuniD· 1 shared Fan ZhangiD· 1 shared Gening JiangiD· 1 shared Huansha YuiD· 1 shared Jian ZhangiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Chunyan WuORCID

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2 papers

Recent·Most cited

Predicting Spatial Transcriptomics from H&E Image by Pretrained Contrastive Alignment Learning

Jiawei Zou, Kai Xiao, Zexi Chen, Jiazheng Pei, Jing Lin Xu, Tao Chen, Likun Hou, Chunyan Wu, Yunlang She, Zhiyuan Yuan, Luonan Chen

This paper introduces CarHE, a method that predicts spatial transcriptomics data from H&E images using contrastive learning, achieving high accuracy and enabling cost-effective analysis.

bioRxiv · Jun 15, 2025 · PreprintBioinformatics

Tertiary Lymphoid Structure and CD8 T Cell Exclusion in Minimally Invasive Adenocarcinoma

Jin Wang, Dongbo Jiang, Xiaoqi Zheng, Wang Li, Tian Zhao, Di Wang, Huansha Yu, Dongqing Sun, Ziyi Li, Jian Zhang, Zhe Zhang, Likun Hou, Gening Jiang, Ke Fei, Fan Zhang, , Peng Zhang

The paper characterizes the tumor microenvironment of early-stage lung adenocarcinoma, identifying tertiary lymphoid structures and CD8 T cell exclusion mediated by follicular regulatory T cells.

iScience · Jan 1, 2021Peer-reviewedGenetic & Genomic Medicine