Ziyi Li

Phosphorylation enables progressive microtubule-associated protein proteolysis and functionalisation during neural development

The paper identifies SRPK-mediated phosphorylation of MAP1S, showing it regulates proteolytic processing and microtubule binding during neurodevelopment.

Large-scale HLA immunopeptidome and interactome profiling in microglia

The paper profiles HLA immunopeptidomes and interactomes in microglia, identifying disease-associated epitopes and their interactions.

Proteomic Analysis of Endemic Viral Infections in Neuronsoffers Insights into Neurodegenerative Diseases

The paper investigates how endemic viral infections alter the neuronal proteome and links these changes to neurodegenerative disease pathways.

ProtPipe: A Multifunctional Data Analysis Pipeline for Proteomics and Peptidomics

ProtPipe is a data analysis pipeline for proteomics and peptidomics that automates processing, quality control, and downstream analysis of mass spectrometry data.

Altered mRNA transport and local translation in iNeurons with RNA binding protein knockdown

This study investigates how knocking down RNA binding proteins affects mRNA transport and local translation in neurons, revealing distinct impacts on neuritic proteome and transcriptome.

Exploit Spatially Resolved Transcriptomic Data to Infer Cellular Features from Pathology Imaging Data}

This paper introduces STpath, a transfer-learning model that uses spatially resolved transcriptomic data to annotate pathology images and classify tumor microenvironments, showing promising performance with limited training data.

Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD

The paper shows that loss of TDP-43 function leads to the expression of de novo proteins from mis-spliced mRNA transcripts in ALS/FTD.

Tertiary Lymphoid Structure and CD8 T Cell Exclusion in Minimally Invasive Adenocarcinoma

The paper characterizes the tumor microenvironment of early-stage lung adenocarcinoma, identifying tertiary lymphoid structures and CD8 T cell exclusion mediated by follicular regulatory T cells.