Weigang Ge

The paper presents a comprehensive spatial proteome map of human tissues and cancers, enabling drug response analysis and target discovery.

This study evaluates blood contamination in nanoparticle-based plasma proteomics, identifies contamination sources, and introduces software to detect and mitigate contamination in clinical samples.

The paper creates a spatially-resolved human brain proteome atlas, revealing protein diversity and functional specialization, and identifies therapeutic targets in epilepsy.

This study identifies a 24-protein panel distinguishing TNBC from other breast cancers and shows proteomics improves drug sensitivity predictions.

The paper constructs a comprehensive mass spectral library for human thyroid tissues to improve the detection of malignant nodules through proteomic analysis.

This paper presents a computational strategy to optimize spectral library size for DIA-MS data, improving peptide and protein identification rates in colorectal and carcinoma samples.