Pathogenic Role of Delta 2 Tubulin in Bortezomib Induced Peripheral Neuropathy
Maria Elena Pero, C Meregalli, Xiaoyi Qu, Grace Ji-eun Shin, Atul Kumar, Matthew Shorey, Melissa M. Rolls, Kurenai Tanji, Thomas H. Brannagan, Paola Alberti, G Fumagalli, Laura Monza, Wesley B. Grueber, Guido Cavaletti, Francesca Bartolini
This study identifies delta 2 tubulin as a key player in bortezomib-induced peripheral neuropathy by showing its role in axonopathy and mitochondrial motility disruption.
Proceedings of the National Academy of Sciences · Jan 19, 2021Peer-reviewedNeuroscience