Francesca Bartolini

This study identifies a mechanism by which α-synuclein and γ-tubulin cooperatively regulate activity-evoked presynaptic microtubule nucleation to control dopamine release.

This paper introduces Carba1, a carbazole-based compound that prevents chemotherapy-induced neuropathy without reducing cancer drug efficacy.

This study shows RhoA signaling has both inhibitory and stimulatory effects on axon development depending on timing, location, and downstream effectors.

This study identifies mDia1/3 and Rho GTPase signaling as critical regulators of presynaptic actin dynamics and endocytosis.

This study shows that Transthyretin (TTR) promotes axon growth by regulating microtubule dynamics and tubulin acetylation, with restoration of acetylated tubulin rescuing defects in TTR knockout mice.

This study shows NSun2 deficiency in AD leads to miR-125b dysregulation and tau hyperphosphorylation, promoting neurodegeneration through epitranscriptomic mechanisms.

This study identifies integrin overexpression as protective against paclitaxel-induced sensory neuron degeneration in Drosophila and mouse models of chemotherapy-induced peripheral neuropathy.

This study identifies delta 2 tubulin as a key player in bortezomib-induced peripheral neuropathy by showing its role in axonopathy and mitochondrial motility disruption.

This study shows that Arfgef1 haploinsufficiency in mice reduces dendritic surface GABAAR and alters endosome composition, leading to increased seizure susceptibility.