Maria Elena Pero

This paper introduces Carba1, a carbazole-based compound that prevents chemotherapy-induced neuropathy without reducing cancer drug efficacy.

This study shows that Transthyretin (TTR) promotes axon growth by regulating microtubule dynamics and tubulin acetylation, with restoration of acetylated tubulin rescuing defects in TTR knockout mice.

This study identifies integrin overexpression as protective against paclitaxel-induced sensory neuron degeneration in Drosophila and mouse models of chemotherapy-induced peripheral neuropathy.

This study identifies delta 2 tubulin as a key player in bortezomib-induced peripheral neuropathy by showing its role in axonopathy and mitochondrial motility disruption.

This study shows that Arfgef1 haploinsufficiency in mice reduces dendritic surface GABAAR and alters endosome composition, leading to increased seizure susceptibility.