Andrew B. Lehr

This study shows that circadian disruption in rats alters the rhythmic expression of clock and memory genes in the hippocampus without changing overall expression levels.

This study identifies high-impact locations in neural networks that can control sequential activity through local synaptic changes.

This study shows how weak neural sequences can overcome competition by increasing connectivity or cooperating with other sequences, affecting their speed and reactivation.

This paper investigates how neural trajectories and their subspaces are dynamically controlled in the central nervous system through mechanisms like gain modulation and clustered inhibition.

The paper shows that correlated asymmetric connectivity in neural networks generates spatiotemporal activity sequences, while symmetric connectivity produces stationary spatial bumps.

The paper shows that spatially heterogeneous inhibition allows sequential neural activity to project onto task-specific subspaces, enabling fast switching controlled by top-down signals.

This study shows that silencing hippocampal CA2 impairs reversal learning in mice, indicating its role in behavioral flexibility during spatial learning.