Author
University of Technology SydneyORCID 0000-0002-1848-2322Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Tingli Qian, Weijin Wang, Shilong Gao…·David A. Baker
CaGE alternates guided structure prediction with sequence redesign, fading guidance each cycle, so sequences recover complex catalytic sites unaided; designed nonheme-iron and PLP-dependent enzymes were active.
Annika Philomin, Ria Sonigra, Sagardip Majumder…·David A. Baker
This paper introduces a generative AI framework for designing transmembrane β-barrel nanopores with customizable properties for ion sensing, DNA translocation, and transport.
Zheng Zhang, Yi‐Kai Liu, Zhuojun Luo…·W. Andy Tao
The paper identifies D2HG and L2HG-induced O-2-hydroxyglutarylation with chiral specificity, revealing inhibitory effects on kinases MRCKA and SLK.