Early-life gut microbiome and stress-axis perturbations dysregulate systemic, mucosal, and brain immunity
Van A. Ortega, Michelle R. Asbury, Colin R. MacKenzie, Fernando Vicentini, Bilal Hafeez, Haonan Duan, Emily M. Mercer, Erik van Tilburg Bernardes, Kristen N. Kalbfleisch, Jumana Samara, Veronika Kuchařová Pettersen, Daniel Figeys, Keith A. Sharkey, Marie‐Claire Arrieta
This study shows that early-life gut microbiome and stress-axis disruptions impair immune and neurodevelopmental health by altering microbial diversity, SCFA production, and neuroimmune responses.
Gut Microbiology · Oct 4, 2025Peer-reviewedMicrobiology