Haonan Duan

This study shows that early-life gut microbiome and stress-axis disruptions impair immune and neurodevelopmental health by altering microbial diversity, SCFA production, and neuroimmune responses.

MetaLab enables comprehensive DDA and DIA metaproteomics analysis by supporting both modes without requiring DDA results, improving peptide identification in human gut microbiome studies.

MetaDIA reduces the search space for DIA gut metaproteomics by prioritizing peptides based on species and functional abundance, achieving results consistent with traditional DDA-based methods.