Author

Colin R. MacKenzie

Heinrich Heine University DüsseldorfORCID 0000-0001-7732-2698Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Bilal HafeeziD· 1 shared Daniel FigeysiD· 1 shared Emily M. MerceriD· 1 shared Erik van Tilburg BernardesiD· 1 shared Fernando VicentiniiD· 1 shared Haonan DuaniD· 1 shared Jörg PietruszkaiD· 1 shared Jumana SamaraiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Bilal HafeezORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 23, 2025

Hoisted by Their Own Petard: Defeating Immunity Protein-Mediated Bacteriocin Resistance

Tim Moritz Weber, Raquel Guadarrama-Gonzalez, Colin R. MacKenzie, Jörg Pietruszka

This study shows that modifying the immunity protein of Pyocin S2 can overcome resistance in Pseudomonas aeruginosa, enabling broader antimicrobial applications.

DOI 10.1101/2025.10.23.684137

bacteria (other)proteomics

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MicrobiologyGut MicrobiologyPeer-reviewedOct 4, 2025

Early-life gut microbiome and stress-axis perturbations dysregulate systemic, mucosal, and brain immunity

Van A. Ortega, Michelle R. Asbury, Colin R. MacKenzie…·Marie‐Claire Arrieta

This study shows that early-life gut microbiome and stress-axis disruptions impair immune and neurodevelopmental health by altering microbial diversity, SCFA production, and neuroimmune responses.

1 citation

mousemetagenomics

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