Effects of alcohol on the transcriptome, methylome, and metabolome of in vitro gastrulating human embryonic cells
Essi Wallén, K. Rämö, Jussi Vehvilainen, Joonas Sokka, Marko Lehtonen, Timo Otonkoski, Ras Trokovic, Pauliina Auvinen, Olli K. Kärkkäinen, Nina Kaminen‐Ahola
This study examines how alcohol exposure affects the transcriptome, methylome, and metabolome of human embryonic cells during gastrulation, identifying key gene and metabolic changes linked to fetal alcohol spectrum disorders.
Disease Models & Mechanisms · May 22, 2025Peer-reviewedGenetics