Author

Marko Lehtonen

University of Eastern FinlandORCID 0000-0002-5611-0466Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Assay:imaging· 1

Frequent Co-Authors

Anastasiia DriuchinaiD· 1 shared Essi WalléniD· 1 shared Jari Antero LaukkaneniD· 1 shared Joonas SokkaiD· 1 shared Jukka E. HintikkaiD· 1 shared Jussi VehvilaineniD· 1 shared K. RämöiD· 1 shared Leo LahtiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSystems Biology

Anastasiia DriuchinaORCID

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2 papers

Recent·Most cited

Systems Biologynpj gut and liver.Peer-reviewedMay 6, 2026

Prebiotic xylo-oligosaccharides for alleviation of hepatic steatosis: Results from a four-month dietary intervention and determinants of response

Jukka E. Hintikka, Perttu Permi, Marko Lehtonen…·Satu Pekkala

This study investigates the effects of xylo-oligosaccharide (XOS) prebiotic on hepatic steatosis in overweight individuals, finding that it reduces harmful gut metabolites and liver fat in responders.

DOI 10.1038/s44355-026-00066-y

humanmetabolomics

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GeneticsDisease Models & MechanismsPeer-reviewedMay 22, 2025

Effects of alcohol on the transcriptome, methylome, and metabolome of in vitro gastrulating human embryonic cells

Essi Wallén, K. Rämö, Jussi Vehvilainen…·Nina Kaminen‐Ahola

This study examines how alcohol exposure affects the transcriptome, methylome, and metabolome of human embryonic cells during gastrulation, identifying key gene and metabolic changes linked to fetal alcohol spectrum disorders.

8 citationstop 1%

humanbulk RNA-seq

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