Olli K. Kärkkäinen

This study uses metabolomics to show that H. meleagridis infection disrupts the cecal host-microbiota metabolic interface, with cloacal vaccination offering better metabolic protection than oral vaccination.

The paper integrates holo-omic data from porcine hosts and gut microbiomes to predict host-microbiome interactions, identifying both known and novel relationships.

This study examines how alcohol exposure affects the transcriptome, methylome, and metabolome of human embryonic cells during gastrulation, identifying key gene and metabolic changes linked to fetal alcohol spectrum disorders.

This study identifies altered blood metabolites in severe AUD patients and links them to psychological symptoms, suggesting new therapeutic targets.

This study shows that antidepressants activate TrkB receptors through physiological changes like hypothermia and reduced energy expenditure, not just pharmacological action.