GeneticsbioRxivPreprint
High genetic loading for schizophrenia predicts poor response to lithium in patients with bipolar disorder: A polygenic score and cross-trait genetic analysis
Azmeraw T. Amare, Klaus Oliver Schubert, Liping Hou…·Gustavo Turecki
This study finds that a higher genetic risk for schizophrenia is linked to poorer lithium response in bipolar disorder patients, suggesting potential for personalized treatment strategies.
DOI 10.1101/209270