Gavin K. Paterson

Benchmarking nanopore-based strategies for antimicrobial resistance prediction

This study benchmarks in silico AMR prediction tools using nanopore data, finding that assembly strategy and data volume impact accuracy, but no tool perfectly matches lab-based AST results.

Analysis of a detoxified Escherichia coli strain for bacteriophage production

This paper evaluates the use of an endotoxin-reduced E. coli strain for phage production, showing it can generate diverse phage with low endotoxin and minimal downstream processing.

Quorum sensing and capsule expression enable subpopulation evasion of phage killing in Escherichia coli ST131: Implications for targeted therapy

This study identifies mechanisms by which E. coli ST131 evades phage killing through quorum sensing and capsule expression, and develops a phage therapy strategy to overcome these defenses in urine-based conditions.