Sean P. McAteer

Analysis of a detoxified Escherichia coli strain for bacteriophage production

This paper evaluates the use of an endotoxin-reduced E. coli strain for phage production, showing it can generate diverse phage with low endotoxin and minimal downstream processing.

Quorum sensing and capsule expression enable subpopulation evasion of phage killing in Escherichia coli ST131: Implications for targeted therapy

This study identifies mechanisms by which E. coli ST131 evades phage killing through quorum sensing and capsule expression, and develops a phage therapy strategy to overcome these defenses in urine-based conditions.

Phage-encoded sRNA counteracts xenogenic silencing in pathogenic E. coli

The paper identifies a prophage-encoded sRNA, HnrS, that counteracts xenogenic silencing by repressing Hha, enabling virulence gene expression in E. coli.