Author

Sophie V. Eastwood

MRC Unit for Lifelong Health and AgeingORCID 0000-0002-1883-8771Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:electronic health records· 1 Research Focus:fine-mapping· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Alain Gerald BertoniiD· 1 shared Albert V. SmithiD· 1 shared Aliki‐Eleni FarmakiiD· 1 shared Allan R LinnebergiD· 1 shared Anne E. JusticeiD· 1 shared Anne Tybjærg‐Hansen· 1 shared Annemari KäräjämäkiiD· 1 shared Anubha MahajaniD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Alain Gerald BertoniORCID

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2 papers

Recent·Most cited

The relationship between glycaemia, cognitive function, structural brain outcomes and dementia: A Mendelian randomization study in the UK Biobank

Victoria Garfield, Aliki‐Eleni Farmaki, Ghazaleh Fatemifar, Sophie V. Eastwood, Rohini Mathur, Christopher T. Rentsch, Spiros Denaxas, Krishnan Bhaskaran, Liam L Smeeth, Nish Chaturvedi

This paper uses Mendelian randomization to examine causal relationships between glycaemia, cognitive function, brain structure, and dementia in UK Biobank data, finding little evidence of causal associations.

Diabetes · Feb 25, 2021Peer-reviewedGenetic & Genomic Medicine

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

Anubha Mahajan, Jennifer Wessel, Sara M. Willems, Wei Zhao, Neil R. Robertson, Audrey Y. Chu, Wei Gan, Hidetoshi Kitajima, Daniel Taliun, Nigel William Rayner, Xiuqing Guo, Yingchang Lu, Man Li, Richard A. Jensen, Yao Hu, , Jun Liu

This study identifies 16 causal coding variants in type 2 diabetes using fine-mapping and shows that one third of signals are false leads.

Nature Genetics · Apr 1, 2018Peer-reviewedGenetics