Author

Jeffrey Alan Lieberman

National Institutes of HealthORCID 0000-0002-1899-1776Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrés Herrero-RuíziD· 1 shared Felipe Cortés‐LedesmaiD· 1 shared J. Terrón-Bautista· 1 shared Pedro Manuel Martínez‐GarcíaiD· 1 shared Silvia Jimeno-GonzáleziD· 1 shared

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2020-2020 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperMolecular Biology

Andrés Herrero-RuízORCID

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1 paper

Recent·Most cited

Control of RNA polymerase II promoter-proximal pausing by DNA supercoiling

Andrés Herrero-Ruíz, Pedro Manuel Martínez‐García, J. Terrón-Bautista, Jeffrey Alan Lieberman, Silvia Jimeno-González, Felipe Cortés‐Ledesma

The paper shows that topoisomerase IIa removes negative DNA supercoiling at promoters, repressing transcription by enforcing Pol II pausing, and reveals this as a novel regulatory mechanism for gene expression.

bioRxiv · May 12, 2020 · PreprintMolecular Biology