Author

J. Terrón-Bautista

Centro Andaluz de Biología Molecular y Medicina Regenerativa

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Molecular Biology· 1

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Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

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Andrés Herrero-RuíziD· 1 shared Felipe Cortés‐LedesmaiD· 1 shared Jeffrey Alan LiebermaniD· 1 shared Pedro Manuel Martínez‐GarcíaiD· 1 shared Silvia Jimeno-GonzáleziD· 1 shared

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Recent·Most cited

Molecular BiologybioRxivPreprintMay 12, 2020

Control of RNA polymerase II promoter-proximal pausing by DNA supercoiling

Andrés Herrero-Ruíz, Pedro Manuel Martínez‐García, J. Terrón-Bautista…·Felipe Cortés‐Ledesma

The paper shows that topoisomerase IIa removes negative DNA supercoiling at promoters, repressing transcription by enforcing Pol II pausing, and reveals this as a novel regulatory mechanism for gene expression.

2 citations

humanDNA methylation

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