Single-cell analysis of chromatin and expression reveals age- and sex-associated alterations in the human heart
David Fraser Read, Gregory T. Booth, Riza M. Daza, Dana L. Jackson, Rula Green Gladden, Sanjay R Srivatsan, Brent Ewing, Jennifer M. Franks, Cailyn H. Spurrell, Anne Roshella Gomes, Diana R. O’Day, Aishwarya A. Gogate, Beth Martin, H. Hanh Larson, Christian Pfleger, , Cole Trapnell
The paper uses single-nucleus ATAC-Seq and RNA-Seq to analyze age and sex differences in human heart cells, identifying gene expression and chromatin changes linked to these factors.
Communications Biology · Aug 26, 2024Peer-reviewedGenomics